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Condition Article

Lupus (systemic lupus erythematosus)

An educational overview of lupus, a long-term autoimmune condition in which the immune system attacks healthy tissue, causing inflammation in different parts of the body.

Chronic DiseaseInternal MedicineDermatologyFull article

Also known as: SLE, systemic lupus, systemic lupus erythematosus, SLE

Educational information only. This explains health information to discuss with a qualified clinician; it is not a diagnosis, prescription, or treatment. Medical Information & Safety.

Overview

Educational academic overview: SLE is a multisystem autoimmune disease with autoantibodies and a relapsing–remitting course. Study material only.

Symptoms

  • tiredness
  • joint pain and swelling
  • skin rashes, including across the cheeks
  • sensitivity to sunlight

Causes

  • autoimmune process with genetic and environmental factors

Risk factors

  • being assigned female and of reproductive age
  • family history
  • certain environmental triggers

Prevention

  • no known prevention; sun protection and following care plans can help manage flares

Emergency warning signs

  • chest pain or difficulty breathing
  • severe headache with confusion
  • signs of a serious flare

Evaluation & tests

Educational note: clinicians assess lupus using symptoms, examination, and blood tests over time. This library does not diagnose.

Treatment education

Educational overview: care is long-term and individualized by specialists. This library does not prescribe.

Self-care

General education: sun protection, rest, and attending review appointments can support living with lupus when advised by a clinician.

When to seek care

Seek professional care for persistent joint pain, unexplained rashes, or ongoing tiredness with other symptoms.

Related topics

Last reviewed: 2026-01-01T00:00:00.000Z